Returning head coach Andy Farrell has included captain Caelan Doris in his Ireland squad for the autumn internationals, but Joe McCarthy misses out.
Doris, who has not played since undergoing shoulder surgery in early May, recently returned to Leinster training, but it remains unclear if he will be fit to face New Zealand in Chicago on 1 November.
Lock McCarthy, however, was not considered after failing to recover from the foot injury he sustained during the first British and Irish Lions Test against Australia in July.
Ulster forward Cormac Izuchukwu and Munster wing Calvin Nash also miss out because of injury, while full-back Hugo Keenan had already been ruled out after undergoing hip surgery following the Lions tour.
Leinster prop Paddy McCarthy – Joe’s younger brother – is the only uncapped player in the 34-man squad, but the Irish Rugby Football Union [IRFU] says uncapped Munster duo Edwin Edogbo and Brian Gleeson and once-capped Connacht wing Shayne Bolton will travel to Chicago as “cover”.
After facing the All Blacks at Soldier Field in a rematch of their 2016 meeting, Ireland host Japan, Australia and world champions South Africa in Dublin.
“There’s an exciting look to the panel and there’s an opportunity for the more experienced players and for those who made their debuts on the summer tour to Georgia and Portugal,” said Farrell, who returns to Ireland duty after taking a sabbatical to lead the Lions tour to Australia.